It happened on Interstate 465 near the 71st Street exit shortly before 3:30 p.m.
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The suspects' vehicle collided with another car on I-465. The person in that vehicle was temporarily trapped and was transported to the hospital with serious injuries.
Two women inside the SUV were arrested. A third person, who knew the women involved, began filming the scene. Police said he caused a commotion and placed him under arrest.
Police have seized electronic equipment out of the suspects' SUV. It's not clear what role, if any, those items played in the incident.
The investigation shut down several lanes of traffic on I-465 during rush hour, but everything has since been reopened.
No names have been released yet.