Arizona Lottery spokeswoman Cindy Esquer says the prize is the fourth largest in U.S. history and the second-largest in Mega Millions history.
The jackpot's cash option works out to about $224 million. Besides the jackpot, prizes range from $2 to $250,000.
The princely sum drew huge interest across the country as thousands of people lined up to buy tickets in 41 states and Washington, D.C., where the game is available.
The winning numbers were 4, 8, 15, 25 and 47, with 42 being the Mega Ball number.