GREEN BAY, Wis. (AP) — Dwight Freeney's cough rumbled through the locker room. As sick as he clearly was, the hardworking defensive end for Indianapolis had every reason to be tired, too.

It's downright disappointing when nothing goes right.

"We've got to get to a point right now where we have to start making plays and don't kill ourselves," Freeney said after the Colts' 34-14 loss to the Green Bay Packers on Sunday.

"They just did good job, but we killed ourselves, I would say. Not to take anything away from them, but we killed ourselves with a lot with penalties."

The Colts were flagged 12 times for 110 yards, Peyton Manning had a pair of interceptions returned for touchdowns and Indianapolis sure looked lost near the season's halfway point.

"We need to find ourselves," said Dominic Rhodes, who ran for 73 yards and two touchdowns with Joseph Addai sidelined with a hamstring injury. "We're not doing what we need to do to win football games. Green Bay is a great team, and if you don't play well and execute, they are going to blow you out like they did today."

Maybe the Packers really did fix the problems that plagued them during a three-game slide before a win against Seattle last week. But it was sure hard to tell against Indianapolis, a model of consistency the past six seasons.

"Everybody said it didn't mean much last week because it was against a third-string quarterback," defensive end Aaron Kampman said. "Today it was against Peyton Manning. You could see he was getting frustrated and animated out there and that's a great thing for us to see."

Yes, Manning was frustrated, but he also didn't get a whole lot of help from a group of receivers frustrated by the Packers' aggressive coverage. Reggie Wayne made two catches for 24 yards. Marvin Harrison added two more for 11 yards and the Colts couldn't get past flag after flag, including one Harrison snagged for a false start penalty.

The Colts also failed to force a turnover despite three fumbles and several deflected passes, and it's clear that Manning can't lift them on his shoulders alone after needing two knee surgeries before the year began.

"We didn't get anything going, and I certainly didn't do enough as quarterback," said Manning, who finished 21-of-42 for 229 yards and no touchdowns. "Disappointing game by us."

Green Bay had 19 first-half first downs, including four on penalties, and the Colts defense stayed on the field more than 20 minutes while Aaron Rodgers completed 13 passes in a row at one point and Ryan Grant added 19 carries in the half.

"For the offense to go out there and move the ball down the field, run the ball with Grant, Rodgers making his throws, and just moving the ball down field and still putting points on the board, it's big for us," cornerback Charles Woodson said. "It keeps us on the sideline, it keeps us fresh."

Rodgers finished 21-of-28 for 186 yards and a touchdown, Grant added 105 yards on 31 carries with a score of his own, and the Packers (4-3) can rest during its upcoming bye week while watching Indianapolis play some more.

The Colts face undefeated Tennessee next Monday night. Green Bay visits the Titans the following week.

By then, the banged up Packers defense could get Pro Bowl cornerback Al Harris (spleen) and safety Atari Bigby (hamstring) back.

"It's just a big confidence boost for our team," Rodgers said. "We really felt like we needed this going into the bye week and then we have a chance to get healthy and hopefully get Al and Atari back. But you can't say enough about Nick Collins and his interception — a game changer."

On the first possession of the second half, Manning looked for Wayne, who was open but couldn't reel in the high throw that tipped off his fingers.

Collins caught it, zigzagged down the field and showed extra patience waiting for teammates Nick Barnett and Tramon Williams to deliver blocks in a 62-yard return that gave Green Bay a 24-7 lead.

"It feels great," Collins said. "I think that changed the whole game."

The defense scored again late in the fourth quarter when safety Aaron Rouse read Manning's eyes at the goal line and stepped in front of a pass intended for Anthony Gonzalez, returning it 99 yards.

"A lot of guys that have been here six, seven years, we've seen this before and we know how to get back from something like this," Freeney said. "Every game's a different game. We're not going to worry about what happened this game — other than the penalties. We'll go back, make our adjustments and we'll move forward."

Notes:@ The only other time Manning had two interceptions returned for TDs in the same game was Sept. 30, 2001, in a 44-13 loss to the Patriots, according to the Elias Sports Bureau. ... Green Bay has won five straight against AFC opponents. ... Rouse's 99-yard TD return matched Tim Lewis' franchise record set Nov. 18, 1984.