HOUSTON -- Garrett Jones and Marcell Ozuna slugged solo home runs to power the Miami Marlins to a 4-2 victory over the Houston Astros and an interleague series sweep on Sunday at Minute Maid Park.

Jones' blast to right field in the first inning, his 11th, capped the Marlins' three-run frame against Astros right-hander Collin McHugh (4-9). With one out in the sixth, Ozuna drilled a hanging slider 411 feet into the left-field seats for his 16th homer, snapping a four-inning span during which McHugh reclaimed his rhythm and kept Miami (51-53) in check.

McHugh struck out nine over 6 1/3 innings, but his rocky first frame proved costly. Before Jones took him deep, McHugh allowed a leadoff single to left fielder Christian Yelich before right fielder Jordany Valdespin followed with a run-scoring triple into the right-field corner.

The early run support proved beneficial for Marlins right-hander Jacob Turner (4-6), whose effectiveness with men on base confounded the Astros (42-63). Turner surrendered a leadoff home run to Astros second baseman Jose Altuve in the first inning, but that was his lone blemish.

Leadoff batters reached base in the third, fourth and fifth innings for the Astros against Turner and were left stranded on each occasion. The Astros finished 0-for-8 with runners in scoring position.

Altuve went 3-for-4 and stroked leadoff singles in the first, third and fifth innings. He was left stranded in scoring position after stealing second base in the third and was erased as part of an inning-ending double play off the bat of Astros left fielder Chris Carter in the fifth.

Astros first baseman Jon Singleton belted a solo home run, his seventh this season, off Marlins closer Steve Cishek with one out in the ninth. Cishek recovered to strike out catcher Carlos Corporan and right fielder Robbie Grossman in succession to record his 26th save on the season.

NOTES: The Astros promoted top pitching prospect Mark Appel, the No. 1 overall pick in the 2013 draft, to Double-A Corpus Christi despite the fact that Appel (2-5, 9.74 ERA) struggled mightily with high Class A Lancaster. Appel threw a bullpen session at Minute Maid Park on Sunday while en route to Corpus Christi. ... Before recording a three-run double that put Miami ahead to stay on Saturday, Marlins DH Giancarlo Stanton had produced just 20 of his 66 RBIs on the road, his 30.3 road percentage ranking as the second-lowest among players with at least 50 RBIs (Rockies OF Charlie Blackmon, 30.2 percent). ... Astros LHP Brett Oberholtzer will start the series opener against the Oakland A's on Monday, having supplanted RHP Brad Peacock in the rotation. Oberholtzer has been solid as the Astros' "sixth" starter, effectively filling in as an injury replacement.