Aside from that achievement, there wasn't much else the White Sox could relish as their quest to seize the American League Central title didn't get any easier.
"It's all about wins and losses," Peavy said. "It wasn't my night. It wasn't our team's night. Ervin Santana had one of those nights he can have. He was awfully good. He shut us down."
Peavy (11-12) is scheduled to make two more starts — against the Indians on Sept. 26 and Oct. 1 — and the Sox need him and his teammates to regain the spark that was noticeably missing after the Tigers' game with the Twins was rained out.
"I feel fine," Peavy said. "I said in spring training I want to make my starts on my turn, I believe I'll contribute if that happens. I believe I've been able to do that so far.
"I need to find a way to win and get this team in the playoffs and have a chance to do what we all came to spring training to do, and that was not to prove anything to anybody. That was to get a chance to win the ultimate prize and why we suit up every day.
"I can sit here and take the blame and certainly will, but we all have to dig deep and try to find a way to beat a good team that is playing for a lot as well."
After pitching a perfect first, Peavy was knocked around, and the damage could have been worse. Mark Trumbo was caught off third and nailed in a rundown for the final out of the second after Kendrys Morales homered to equalize Alejandro De Aza's leadoff homer.
The Angels snapped the 1-1 tie in the third on Albert Pujols' two-run bloop single in which center fielder De Aza accidentally kicked the ball to enable Mike Trout to score from second.
Trout hit his 28th home run in the seventh off Brian Omogrosso to become the first AL rookie to score 120 runs in a season since the Mariners' Ichiro Suzuki in 2001.
The offense was lifeless after De Aza hit his second leadoff home run in four games. Santana, who entered Friday's game with a 5.08 ERA and hadn't pitched since Sept. 12, tied a career high with 11 strikeouts and allowed only two hits in seven innings.
"We got our rear ends kicked," manager Robin Ventura said.
Alex Rios typified the Sox's frustration in the seventh when Santana robbed him of a hit, causing Rios to spike his bat while running to first.
"That was the best I've seen (Santana) pitch," Paul Konerko said.
The Sox's best shot occurred in the eighth after Gordon Beckham hit an RBI single off reliever Kevin Jepsen. But left-hander Scott Downs struck out Adam Dunn with runners on first and third to end the rally.
Unlike Thursday's loss to the Royals in Kansas City in which the Sox failed to expand a 3-0 lead, they were at full strength with the return of cleanup hitter Konerko.
Konerko had played in 31 consecutive games before suffering back stiffness that sidelined him Thursday. Konerko handled the designated-hitter duties Friday night, but Ventura said it was only "possible" that Konerko would return to first base Saturday night, partly because Ventura likes how Adam Dunn has fared at first.
"I can do either," Konerko said before the game. "Whatever they want to make the lineups, I'm ready to play first."